Juvenile xanthogranuloma with recurrent subdural effusions

Abstract
A 2 yr old girl with extensive cutaneous xanthogranuloma and recurrent subdural effusions was investigated. Differentiation from histiocytosis X depended upon light microscopical and EM studies of the cutaneous infiltrate and cells obtained from the CSF. The recurrent subdural effusions responded well to cranial irradiation. Although juvenile xanthogranuloma is generally a benign cutaneous disorder, a spectrum of nevoid proliferative changes involving systemic organs may occur.