PHOTOMODIFICATION OF BIOLOGICAL MEMBRANES WITH EMPHASIS ON SINGLET OXYGEN MECHANISMS
- 1 July 1987
- journal article
- review article
- Published by Wiley in Photochemistry and Photobiology
- Vol. 46 (1), 147-160
- https://doi.org/10.1111/j.1751-1097.1987.tb04749.x
Abstract
This review discusses photomodification of biological membranes and model membrane systems. Current concepts of membrane structure are first reviewed briefly. The role of preillumination association of sensitizer with membranes as it relates to photomodification rate is discussed, as well as the role of singlet oxygen in membrane photomodification. Finally the characteristics of singlet oxygen generation in membranes are considered. The evidence clearly indicates that membrane photomodification cannot be understood based only on the properties of sensitizers and singlet oxygen in aqueous solution. Rather the properties of sensitizers in association with membranes are the determinants of membrane photomodifcation. These properties differ significantly in aqueous solution and in membranes.Keywords
This publication has 123 references indexed in Scilit:
- Photodynamic damage to plant leaf tissue by rose bengalPlant Science Letters, 1984
- Hematoporphyrin photosensitization of epidermal microsomes results in destruction of cytochrome P-450 and in decreased monooxygenase activities and heme contentBiochemical and Biophysical Research Communications, 1982
- Erythrosine B (Red dye no. 3) mediated oxidation-reduction in brain membranesBiochemical and Biophysical Research Communications, 1980
- TYPE I AND TYPE II MECHANISMS IN THE PHOTOOXIDATION OF L‐TRYPTOPHAN AND TRYPTAMINE SENSITIZED BY HEMATOPORPHYRIN IN THE PRESENCE AND ABSENCE OF SODIUM DODECYL SULPHATE MICELLESPhotochemistry and Photobiology, 1980
- Perturbations of membrane structure by optical probes: I. Location and structural sensitivity of merocyanine 540 bound to phospholipid membranesThe Journal of Membrane Biology, 1980
- A SURVEY OF IN VIVO PHOTODYNAMIC ACTIVITY OF XANTHENES, THIAZINES, AND ACRIDINES IN YEAST CELLSPhotochemistry and Photobiology, 1977
- Reactivity of singlet molecular oxygen with cholesterol in a phospholipid membrane matrix. A model for oxidative damage of membranesBiochemical and Biophysical Research Communications, 1977
- Singlet oxygen in biological systemsTrends in Biochemical Sciences, 1977
- Optical probes of membrane potentialThe Journal of Membrane Biology, 1976
- Photodynamic action of protoporphyrin IX on human erythrocytes: Cross-linking of membrane proteinsBiochemical and Biophysical Research Communications, 1976