Primary lymphoma of the liver is extremely rare, and is more common among immunocompromised patients. It typically occurs during the fifth decade of life and has a male predominance. Abdominal pain, weight loss, and fever are the normal symptoms. Liver function tests are usually upset. Ultrasonography, computed tomography, and magnetic resonance imaging can help in the diagnosis, which can be confirmed only by histological examination of a liver biopsy specimen. Treatments include surgery, chemotherapy, and radiotherapy all of which give good results. Surgical resection when feasible is beneficial.