SICKLE CELL-HEMOGLOBIN C DISEASE

Abstract

A case of sickle cell-hemoglobin C disease in an adult Negro male is reported. Pertinent features of the case being an asymptomatic course; a moderate normochromic anemia; many target cells in the peripheral blood; a combination of the 2 abnormal hemoglobins (sickle hemoglobin and hemoglobin C) demonstrated by electrophoresis; and X-ray changes of a sclerotic nature in the bones. There is included a study of the family of the case reported with some comments about the hereditary aspects of this hemoglobin abnormality.