The Biologic Effects of D-Thyroxine
- 1 February 1962
- journal article
- research article
- Published by SAGE Publications in Angiology
- Vol. 13 (2), 85-88
- https://doi.org/10.1177/000331976201300207
Abstract
Comparison of D- and L-thyroxine for calorigenicity, antigoitrogenicity, effect on metamorphosis of the tadpole, effects on cholesterol metabolism, cardiac effects, tissue localization, and toxicity reveals a quantitative and useful separation of biological effects. Tests in the mouse, rat, rabbit, and dog provide a basis for the selection of a dose of D-thyroxine which will decrease serum and liver cholesterol concentrations markedly in man without noticeable calorigenic, cardiac, or toxic effects.Keywords
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- Oxygen Consumption by Tissues from Rats injected with L- or D-ThyroxineNature, 1960
- Physiological disposition of d- and l-thyroxine in the ratAmerican Journal of Physiology-Legacy Content, 1959