Dendritic Cells Can Initiate Protective Immune Responses against Malaria
Open Access
- 1 August 2001
- journal article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 69 (8), 5173-6
- https://doi.org/10.1128/iai.69.8.5173-5176.2001
Abstract
An understanding of the antigen presentation mechanisms that mediate induction of protective immune responses against malaria is essential for the development of successful immunization approaches. Here we show that dendritic cells presentingPlasmodium yoeliisporozoite antigens are able to activate specific CD4+and CD8+T cells and initiate protective immune responses against malaria in mice.Keywords
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