Local Factors in Ascites Formation during Sodium Retention in Cirrhosis

Abstract

PREVIOUS studies have indicated that in patients with cirrhosis the presence or absence of ascites can be explained by a consideration of hydrostatic and osmotic forces, and a similar analysis can be used to explain the responses to various forms of treatment.^{1 , 2} It is well established that, in cirrhosis, an increased intake of sodium causes an increased rate of ascites formation,³ but the precise local forces leading to the transfer of fluid across the peritoneal membrane under these conditions have not been defined. The present study was undertaken to provide such information.Patients and MethodsFour patients with portal cirrhosis . . .