Catalytic Asymmetric Syntheses of ICI-199441 and CP-99994 Using Nitro-Mannich Reaction
- 1 March 2002
- journal article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 31 (3), 276-277
- https://doi.org/10.1246/cl.2002.276
Abstract
No abstract availableThis publication has 14 references indexed in Scilit:
- Stereoselective synthesis of (+)-CP-99,994: A substance P non-peptide antagonistTetrahedron Letters, 1999
- The Nitro-Mannich Reaction and Its Application to the Stereoselective Synthesis of 1,2-DiaminesThe Journal of Organic Chemistry, 1998
- The Chemistry of Vicinal DiaminesAngewandte Chemie International Edition, 1998
- Isothiocyanate-Substituted .kappa.-Selective Opioid Receptor Ligands Derived from N-Methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]phenylacetamideJournal of Medicinal Chemistry, 1994
- Anti-emetic profile of a non-peptide neurokinin NK1 receptor antagonist, CP-99,994, in ferretsEuropean Journal of Pharmacology, 1993
- Synthesis, in vitro binding profile, and autoradiographic analysis of [3H]-cis-3-[(2-methoxybenzyl)amino]-2-phenylpiperidine, a highly potent and selective nonpeptide substance P receptor antagonist radioligandJournal of Medicinal Chemistry, 1993
- Synthesis of (±)-CP-99994: A highly potent substance P antagonistTetrahedron Letters, 1993
- Discovery of a potent substance P antagonist: recognition of the key molecular determinantJournal of Medicinal Chemistry, 1992
- Structure activity studies related to 2-(3,4-dichlorophenyl)-N-methyl-N-[2-(1-pyrrolidinyl)-1-substituted-ethyl]acetamides: a novel series of potent and selective .kappa.-opioid agonistsJournal of Medicinal Chemistry, 1991
- 2-(3,4-Dichlorophenyl)-N-methyl-N-[2-(1-pyrrolidinyl)-1-substituted-ethyl]-acetamides: the use of conformational analysis in the development of a novel series of potent opioid .kappa. agonistsJournal of Medicinal Chemistry, 1991