Abstract
The glycogen, lactic acid, and creatine phosphate content of the submaxillary glands of the dog were detd. in resting glands (i) and in glands exhausted by simultaneous stimulation of sympathetic and parasym-pathetic nerve supply (ii). In (ii) there was an average of 41% less glycogen, 128% more lactic acid, and 63% less creatine phosphate than in (i). Separate stimulation of the chorda tympani and the sympathetic supply gave smaller changes. The energy metabolism of the gland is apparently similar to that of muscle.

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