Potential Compounds for Monitoring Method Performance in the Determination of Selected Organochlorine Pesticides and Polychlorinated Biphenyls in Human Serum*

Abstract

Four compounds—2,2′,3,4′-tetrechlorobiphenyl, decachlorodiphenylether, 1,1-dichloro-2,2-bis(p-ethylphenyl)ethane, and dichlorobenzophenone—are recommended for monitoring the within-sample behavior of an analytical method that quantifies chlorinated pesticides and polychlorinated biphenyls (such as Aroclor 1260) in serum using packed column gas chromatography with electron capture detection. Percent recoveries of these surrogates averaged >80%, except with dichlorobenzophenone, which had an average recovery of >70%.