PULMONARY ARTERIAL PRESSURE AFTER PRISCOLINE IN MITRAL STENOSIS

Abstract
The effects of priscoline, 25 mg intravenously introduced by catheterization, on the pulmonary and brachial arterial pressure and oxygen saturation, cardiac output and vascular resistances were studied in 14 patients with mitral stenosis. The drug caused a significant fall in pulmonary artery pressure, while the fall in the peripheral arterial pressure was much less pronounced. Priscoline through its sympathicolytic and adrenolytic effect apparently diminishes pulmonary arteriolar spasm present in cases of mitral stenosis with pulmonary hypertension.