THE EFFECT OF EPINEPHRIN ON MUSCLE GLYCOGEN IN THE ABSENCE OF THE LIVER, AND A MODIFICATION OF THE OPERATION FOR LIVER REMOVAL

Abstract

The liver was totally extirpated in 14 cats to determine if a decrease of muscle glycogen would follow, indicating a peripheral action of epinephrine on carbo-hydrates. No sign of peripheral action of epinephrine was obtained, either on muscle glycogen or on the rate at which glucose leaves the blood (the latter confirming the work of Soskin). These results differ from the work of Cori and Cori, possibly, it is suggested, because of technic and because of the difference between the rat and the cat.