Induction of leukemia by both fractionated x-irradiation and radiation leukemia virus involves loci in the chromosome 2 segment H-30-A.
Open Access
- 1 January 1983
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 80 (2), 462-466
- https://doi.org/10.1073/pnas.80.2.462
Abstract
A common link between the induction of leukemia by (i) fractionated doses of x-irradiation and (ii) radiation leukemia virus in mice may be established by the observation that the segment of chromosome 2 between the loci for the minor histocompatibility antigen H-30 and color coat agouti (H-30-A) includes distinct loci involved in susceptibility to leukemogenesis induced by factors i and ii.Keywords
This publication has 21 references indexed in Scilit:
- Evidence for a major cluster of lymphocyte differentiation antigens on murine chromosome 2.Proceedings of the National Academy of Sciences, 1982
- Endogenous MuLV infection does not contribute to onset of radiation- or carcinogen-induced murine thymoma.1982
- Functional properties of Ly 11.2 lymphocytes: a role for these cells in leukemia?The Journal of Immunology, 1980
- Physicochemical, biological and serological properties of a leukemogenic virus isolated from cultured radl-V-induced lymphomas of C57BL/Ka miceVirology, 1978
- Experimental models and conceptual approaches to studies of lymphomas and leukemia: etiology, biology, and control.1978
- Increased synthesis and expression of H-2 antigens on thymocytes as a result of radiation leukemia virus infection: a possible mechanism for H-2 linked control of virus-induced neoplasia.The Journal of Experimental Medicine, 1978
- Biological and serological characterization of radiation leukemia virus.Proceedings of the National Academy of Sciences, 1976
- Radiation leukemia in C57BL/6 mice. I. Lack of serological evidence for the role of endogenous ecotropic viruses in pathogenesis.The Journal of Experimental Medicine, 1976
- RECOMBINANT-INBRED STRAINS AN AID TO FINDING IDENTITY, LINKAGE, AND FUNCTION OF HISTOCOMPATIBILITY AND OTHER GENESTransplantation, 1971
- On the natural history of the murine leukemias: presidential address.1967