KINETIC EQUATIONS FOR ENZYME REACTIONS IN THE PRESENCE OF POWERFUL INHIBITORS
- 1 August 1959
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 37 (8), 1268-1271
- https://doi.org/10.1139/v59-188
Abstract
Steady-state equations are worked out for the case of a competitive inhibitor that is present in concentrations comparable with that of the enzyme; allowance is made for the inhibitor attached to the enzyme. Two cases are considered: in case 1 the enzyme and inhibitor form a simple addition complex, while in case 2 a molecule is split off. Methods of graphical analysis of rate data are described.This publication has 3 references indexed in Scilit:
- Kinetics of Carboxypeptidase Action. I. Effect of Various Extrinsic Factors on Kinetic Parameters1Journal of the American Chemical Society, 1951
- MODE OF INHIBITION OF CHYMOTRYPSIN BY DIISOPROPYL FLUOROPHOSPHATE .2. INTRODUCTION OF ISOPROPYL AND ELIMINATION OF FLUORINE AS HYDROGEN FLUORIDE1950
- ACETYLCHOLINESTERASE .8. DISSOCIATION CONSTANTS OF THE ACTIVE GROUPS1950