A New Regulatory Protein that Affects the State of Actin Polymerization1
- 1 April 1981
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Biochemistry
- Vol. 89 (5), 1655-1658
- https://doi.org/10.1093/oxfordjournals.jbchem.a133363
Abstract
A new protein factor that regulates the state of actin polymerization was purified from porcine brain by DNase I-agarose chromatography. The purified protein factor consisted of a 1: 1 complex of 88, 000 dalton polypeptide and actin. When actin was polymerized by salt in the presence of the factor, the steady-state viscosity and the sedimentability were greatly reduced. The extent of the reductions was found to be greater in the presence of Ca2+ than in its absence.This publication has 14 references indexed in Scilit:
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