ON THE COMPARATIVE LUTEINIZING CAPACITY OF THE URINE OF PREGNANCY AND OF THE MENOPAUSE

Abstract

Urines of pregnancy and menopause were administered to infantile and adult rats. Ovaries were examined and sectioned 4-7 days later. Qlut (coef. of luteinization) = l/n-1000 where l=mgm. of luteal tissue produced and n = quantity of urine injected in cc. Using small amts. of pregnancy urine the Qlut was as great as 8000-9000. Greater quantities did not increase luteal tissue in linear proportion. The urine of menopause of 5 of 6 women produced luteinization when sufficient quantities were administered. The Qlut varied from 2 to 100.