Localization of the HST/FGFK gene with regard to 11 q 13 chromosomal breakpoint and fragile site

Abstract
The HST/FGFK gene, a member of the fibroblast growth factor gene family and a protooncogene, is localized on chromosomal band 11 q 13. Genes in this region are frequently involved in hematopoietic and solid tumors. Here we show that the HST gene lies telomeric to the BCLI gene, the t(l I;14)(q13;q32) breakpoint, and the FRAIIA rare fragile site.