Cardiovascular and Renal Complications of Cushing's Syndrome

Abstract

CARDIOVASCULAR and renal changes are frequently important features of Cushing's syndrome. Of the 12 cases reported by Cushing¹ in 1932, hypertension occurred in 9, and cardiac hypertrophy in 4. Friedberg² has stressed the fact that the most important finding so far as the vascular system is concerned is hypertension, which may be severe and associated with cardiac enlargement, cerebral hemorrhage and renal insufficiency. In a review of 67 cases of Cushing's syndrome compiled from the literature, Eisenhardt and Thompson³ found hypertension in 57 cases, and Cope and Raker⁴ described significant hypertension in approximately half of 46 cases and mild or . . .