Declining Growth Rate of West Nile Virus in North America
- 1 March 2007
- journal article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 81 (5), 2531-2534
- https://doi.org/10.1128/jvi.02169-06
Abstract
To determine the demographic history of West Nile virus (WNV) in North America, we employed a coalescent method to envelope coding region data sets for the NY99 and WN02 genotypes. Although the observed genetic diversities in both genotypes were of approximately the same age, the mean rate of epidemiological growth of the WN02 population was approximately three times that of the NY99 population, a finding compatible with the recent dominance of the former genotype. However, there has also been a marked decrease in the recent growth rate of WN02, suggesting that WNV has reached its peak prevalence in North America.Keywords
This publication has 10 references indexed in Scilit:
- A live, attenuated recombinant West Nile virus vaccineProceedings of the National Academy of Sciences, 2006
- Relaxed Phylogenetics and Dating with ConfidencePLoS Biology, 2006
- Phylogenetic analysis of North American West Nile virus isolates, 2001–2004: Evidence for the emergence of a dominant genotypeVirology, 2005
- Epidemiology and Transmission Dynamics of West Nile Virus DiseaseEmerging Infectious Diseases, 2005
- GENETIC AND PHENOTYPIC VARIATION OF WEST NILE VIRUS IN NEW YORK, 2000–2003The American Journal of Tropical Medicine and Hygiene, 2004
- A Large Variation in the Rates of Synonymous Substitution for RNA Viruses and Its Relationship to a Diversity of Viral Infection and Transmission ModesMolecular Biology and Evolution, 2004
- Virus Detection Protocols for West Nile Virus in Vertebrate and Mosquito SpecimensJournal of Clinical Microbiology, 2003
- Rates of Molecular Evolution in RNA Viruses: A Quantitative Phylogenetic AnalysisJournal of Molecular Evolution, 2002
- Origin of the West Nile Virus Responsible for an Outbreak of Encephalitis in the Northeastern United StatesScience, 1999