Life Span of the Rat Red Blood Cell as Determined by Glycine-2-C14
- 1 June 1951
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 165 (3), 565-567
- https://doi.org/10.1152/ajplegacy.1951.165.3.565
Abstract
Ten adult male rats were given 10 [mu]c (0.82 mg.) of C14 as glycine-2-C14 intraperit. Hemoglobin was extracted from the cells by a modification of the method of Drabkin. This was combusted to CO2 by the method of Van Slyke and Folch. The specific activity of the CO2 was measured in a 100-cc. ionization chamber. The avg. life span of the red blood cells was 68 days and 50% of the cells were destroyed within the 59th to 77th days.Keywords
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