Liver-specific Inducible Nitric-oxide Synthase Expression Is Sufficient to Cause Hepatic Insulin Resistance and Mild Hyperglycemia in Mice
Open Access
- 1 October 2011
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 286 (40), 34959-34975
- https://doi.org/10.1074/jbc.m110.187666
Abstract
No abstract availableKeywords
This publication has 53 references indexed in Scilit:
- Phosphoproteomic Analysis Identifies Grb10 as an mTORC1 Substrate That Negatively Regulates Insulin SignalingScience, 2011
- Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesisProceedings of the National Academy of Sciences, 2010
- Double-Stranded RNA-Dependent Protein Kinase Links Pathogen Sensing with Stress and Metabolic HomeostasisCell, 2010
- Akt2 Is Required for Hepatic Lipid Accumulation in Models of Insulin ResistanceCell Metabolism, 2009
- Increased basal level of Akt-dependent insulin signaling may be responsible for the development of insulin resistanceAmerican Journal of Physiology-Endocrinology and Metabolism, 2009
- Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 DiabetesProceedings of the National Academy of Sciences, 2009
- Acute physical exercise reverses S‐nitrosation of the insulin receptor, insulin receptor substrate 1 and protein kinase B/Akt in diet‐induced obese Wistar ratsThe Journal of Physiology, 2008
- Continuous fat oxidation in acetyl–CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivityProceedings of the National Academy of Sciences, 2007
- Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistanceProceedings of the National Academy of Sciences, 2006
- A new mathematical model for relative quantification in real-time RT-PCRNucleic Acids Research, 2001