Trisomy 16p in a liveborn infant and a review of partial and full trisomy 16.

Abstract
An abnormal female infant, who survived for 10 mo. with almost complete trisomy 16p and monosomy of sub-band 21q22.3, is described. The chromosome anomaly was the result of an unbalanced segregation of a maternal balanced translocation t(16;21)(p11;q22.3). The partial monosomy apparently had little or no adverse phenotypic effect. Cases with trisomy of chromosome 16 material are reviewed. Full trisomy 16 apparently always results in early spontaneous abortion, while trisomy 16p or 16q may be compatible with limited postnatal survival.