Anticoccidials. V. Synthesis and anticoccidial activity of 2(1H)-pyrazinone 4-oxide derivatives.
- 1 January 1980
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 28 (9), 2734-2747
- https://doi.org/10.1248/cpb.28.2734
Abstract
A series of 1-, 3-, 5- and 6-substituted 2(1H)-pyrazinone 4-oxides were synthesized and tested for anticoccidial activity. Of the compounds tested, 1-(.beta.-D-ribofuranosyl)-(22), 1-(2,3,5-tri-O-benzoyl-.beta.-D-ribofuranosyl)-(21) and 1-(2,3,5-tri-O-acetyl-.beta.-D-ribofuranosyl)-2(1H)-pyrazinone 4-oxides (24) showed high activity.This publication has 4 references indexed in Scilit:
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