Dose‐response studies with pancuronium, vecuronium and their combination.
Open Access
- 1 December 1984
- journal article
- research article
- Published by Wiley in British Journal of Clinical Pharmacology
- Vol. 18 (6), 947-950
- https://doi.org/10.1111/j.1365-2125.1984.tb02568.x
Abstract
Pancuronium, vecuronium and a combination of these were administered in an incremental fashion to study any potentiation of effect with the combination of the two relaxants. The ED95 (dose producing a 95% block) of the combination was 29 micrograms kg-1 for each component in comparison to 57 micrograms kg-1 for vecuronium and 59 micrograms kg-1 for pancuronium. The dose-response curves for the three groups did not differ from each other and no potentiation was demonstrated.This publication has 9 references indexed in Scilit:
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