[ 3 H]Lysergic Acid Diethylamide: Cellular Autoradiographic Localization in Rat Brain
- 10 September 1971
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 173 (4001), 1022-1024
- https://doi.org/10.1126/science.173.4001.1022
Abstract
Intravenous administration of [3H]lysergic acid diethylamide(LSD) to rats resulted in accumulation of the drug in the brain within 15 minutes. Autoradiographic methods were used to differentiate free and bound [3H]LSD in brain tissue.Free [3H]LSD was generally distributed in the pituitary and pineal glands, cerebellum, hippocampus,and choroid plexus.Bound [3H]LSD was localized in neurons of the cortex, caudate nucleus, midbrain, and medulla,as well as in choroid plexus epithelium.Keywords
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