THE FUNCTION OF THE GOLGI COMPLEX IN TRANSITIONAL EPITHELIUM
Open Access
- 1 September 1966
- journal article
- research article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 30 (3), 623-643
- https://doi.org/10.1083/jcb.30.3.623
Abstract
The superficial squamous cells of rat transitional epithelium are limited, on their luminal face, by an asymmetrically thickened membrane. Patches of similar thick membrane are found in the walls of the Golgi cisternae and it is suggested that the Golgi system is the site of assembly of the thick plasma membrane. This implies membrane flow from the Golgi apparatus to the cell surface, and there is indirect evidence that the membrane is transported in the form of fusiform vacuoles, derived from the Golgi cisternae, which fuse with, and become part of, the free cell membrane. Uptake of injected Imferon shows that similar, large, thick-walled vacuoles may be formed by invagination of the free cell surface. Some of these vacuoles are subsequently transformed into multivesicular bodies and autophagic vacuoles. The formation of other large heterogeneous bodies is described, and some of these are shown to have acid phosphatase activity.This publication has 12 references indexed in Scilit:
- ORIGIN OF GRANULES IN POLYMORPHONUCLEAR LEUKOCYTESThe Journal of cell biology, 1966
- THE PERMEABILITY OF RAT TRANSITIONAL EPITHELIUMThe Journal of cell biology, 1966
- THE FINE STRUCTURE OF THE TRANSITIONAL EPITHELIUM OF RAT URETERThe Journal of cell biology, 1965
- FINE STRUCTURE OF PARENCHYMAL CELL OF NORMAL RAT LIVER .I. GENERAL OBSERVATIONS1965
- LYTIC ACTIVITIES IN RENAL PROTEIN ABSORPTION DROPLETSThe Journal of cell biology, 1964
- YOLK PROTEIN UPTAKE IN THE OOCYTE OF THE MOSQUITO AEDES AEGYPTI. LThe Journal of cell biology, 1964
- Origin of the Golgi system in amoebaeCell and tissue research, 1964
- CYTOCHEMISTRY AND ELECTRON MICROSCOPYThe Journal of cell biology, 1963
- AN OBSERVATION ON THE FUNCTIONING OF THE GOLGI APPARATUSThe Journal of cell biology, 1963
- IMPROVEMENTS IN EPOXY RESIN EMBEDDING METHODSThe Journal of cell biology, 1961