SHORT TERM EFFECTS OF TIMOLOL IN CHRONIC GLAUCOMA

Abstract
Patients (15) with glaucomatous field defects in at least 1 eye were subjected to computerized perimetry and IOP [intraocular pressure], systemic blood pressure and pulse rate measurements before and after timolol or placebo instillation in both eyes. A significant decrease of IOP and pulse rate was found 2 h after timolol. The visual fields were not improved; the correlation between IOP and visual field performance being (though not significantly) positive. The lack of improvement could not be attributed to the decrease in pulse rate.