The effect of atropine on acetylcholine action at the neuromuscular junction
- 27 November 1973
- journal article
- Published by The Royal Society in Proceedings of the Royal Society of London. B. Biological Sciences
- Vol. 184 (1075), 221-226
- https://doi.org/10.1098/rspb.1973.0046
Abstract
The action of atropine at the motor end plate was studied by measuring its effect on acetylcholine-induced fluctuations of membrane potential ('acetylcholine noise'). Atropine, in contrast to curare, modifies the elementary depolarization produced by the impact of acetylcholine molecules; it reduces the voltage amplitude and shortens the underlying ionic current pulse.Keywords
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