Heterocycles 2: Synthesis of 1-Hydroxycarbazoles and Mukonine Isomers

Abstract

Cyclohexan-1'',2''-dione-1''-diazabenzoic acids obtained from diazotised aminobenzoic acids and 2-hydroxymethylenecyclohexanone on cyclization afford 1-oxo-1,2,3,4-tetrahydrocarbazole derivatives. These on esterification followed by aromaisation and methylation gave the Mukonine isomers, 19, 20 and 22.