Serine Transhydroxymethylase Activity in Vertebrate Retina
- 1 September 1982
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 39 (3), 743-746
- https://doi.org/10.1111/j.1471-4159.1982.tb07955.x
Abstract
The presence of serine transhydroxymethylase (STHM; EC 2.1.2.1) in crude homogenates of rat, guinea pig and goat retina was demonstrated. There was a variation in the levels of retinal STHM activity in the 3 spp. Substantial STHM activity was found in all the 3 retinal preparations in the absence of pyridoxal-5-phosphate in the incubation medium. There was direct correlation (r = 0.995; P < 0.001) between the STHM activity and the glycine content in rat telencephalon, midbrain, medulla-pons, spinal cord and retina. STHM is apparently an important enzyme for the synthesis of neural glycine in the vertebrate retina.Keywords
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