Malignant Transformation of Hamster Brain Cells in Vitro by Human Papovavirus BK 2
- 1 March 1976
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 56 (3), 671-673
- https://doi.org/10.1093/jnci/56.3.671
Abstract
Human papovavirus BK caused the malignant transformation in vitro of brain cells pr~pared from newborn hamsters. The transformed cells produced BK virus T antigen and grew as tumors after sc inoculation into hamsters that developed antibodies to BK virus T antigen. The histopathology of the tumors revealed an undifferentiated glioma.Keywords
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