SUPPRESSION OF SERUM FOLLICLE STIMULATING HORMONE IN INTACT AND ACUTELY OVARIECTOMIZED RATS BY PORCINE FOLLICULAR FLUID
- 1 November 1977
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 101 (5), 1639-1642
- https://doi.org/10.1210/endo-101-5-1639
Abstract
Sham ovariectomy (SOV) or ovariectomy (OVX) was performed at 0800h of metestrus; porcine serum (PS) or porcine follicular fluid (PFF) was injected i.p. at 0830h and/or 1130h, with terminal blood samples collected at 1700h. Fluid from medium and large follicles in porcine ovaries, charcoal extracted to remove steroids, significantly reduced serum FSH [follicle stimulating hormone], in a dose-dependent manner. The SOV rats were more sensitive to PFF with respect to serum FSH lowering than the OVX rats, although when enough PFF was injected, both groups showed the same level of suppression. Since serum LH was very low, the possible effect of PFF on this hormone could not be assessed.This publication has 5 references indexed in Scilit:
- The Role of Adrenal and Ovarian Steroids in the Control of Serum LH and FSHEndocrinology, 1977
- Acute Changes in Serum Gonadotrophins and Steroids Following Orchidectomy in the Rat: Role of the Adrenal Gland1Endocrinology, 1977
- Inhibition of Oocyte Maturation by Porcine Follicular Fluid: Partial Characterization of the Inhibitor1Biology of Reproduction, 1976
- Hypothalamic Regulation of Pituitary FSH SecretionEndocrinology, 1976
- Differentiation Between Neural and Hormonal Control of Sexual Behavior and Gonadotrophin Secretion in the Female RatEndocrinology, 1976