Enzymes and catalysts. I. Pig liver esterase-catalyzed hydrolysis of heterocycli diesters.

Abstract

The asymmetric hydrolysis of five-membered cyclic diesters was carried out by using pig liver esterase (PLE) as a catalyst. The absolute configurations of the resulting half esters and recovered diesters were established and the stereospecificity of PLE action in such systems was revealed.