Effects of Human Menopausal Gonadotrophin on a Eunuchoidal Male

Abstract

OLIGOSPERMIA is a common clinical problem, affecting about 10 to 15 per cent of healthy males.¹ Several factors responsible for the maintenance of normal spermatogenesis have been determined, but in most of the cases that occur in clinical practice no known cause can be elucidated, precluding any rational treatment. It is apparent that more information is required about the normal physiology of spermatogenesis.Heller and Nelson² showed that spermatogenesis could be produced in eunuchoidal males by the use of chorionic gonadotrophin combined with biologic extracts having FSH (follicle-stimulating-hormone) activity. The use of human pituitary gonadotrophins to restore spermatogenesis in a . . .