Protein Synthesis by Heart Muscle Ribosomes: An Effect of Insulin Independent of Substrate Transport
- 14 October 1966
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 154 (3746), 284-285
- https://doi.org/10.1126/science.154.3746.284
Abstract
Ribosomes from heart muscle of diabetic animals perfused for 15 minutes with insulin, but without added substrate, were more active in the catalysis of protein synthesis than were ribosomes from hearts perfused without insulin. This effect of insulin on the efficiency of protein synthesis seems not to result from transport of some critical substrate into muscle, nor is the effect on ribosomes mediated by a product of a tissue other than muscle.Keywords
This publication has 8 references indexed in Scilit:
- Effect of insulin and diabetes on protein synthesis by ribosomes from heart muscleAmerican Journal Of Medicine, 1966
- Accumulation of amino acids in muscle of perfused rat heart. Effect of insulinBiochemical Journal, 1965
- Protein Synthesis by Ribosomes from Heart Muscle: Effect of Insulin and DiabetesScience, 1965
- Isolation and characterization of ribonucleoprotein particles from heart muscleBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1965
- Separation of the Effects of Growth Hormone on Muscle Amino Acid Transport and Protein SynthesisEndocrinology, 1964
- Regulation of Glucose Uptake in MuscleJournal of Biological Chemistry, 1961
- Stimulation of amino acid transport by insulin in the isolated rat diaphragmBiochimica et Biophysica Acta, 1958
- Untersuchungen uber die Harnstoffbildung im TierkörperHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1932