Inhibition of replication of human immunodeficiency virus by a heteropolyoxotungstate (PM-19).
- 31 December 1989
- journal article
- letter
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 38 (1), 285-287
- https://doi.org/10.1248/cpb.38.285
Abstract
A Keggin polyoxotungstate PM-19 K7[PTi2W10040].cntdot.6H2O was found to be a potent inhibitor of the replication of human immunodeficiency virus (HIV), which causes acquired immunodeficiency syndrome (AIdS), in OKT4+ cells. In contrast, the effect of HPA 23 (NH4)17Na[NaSb9W21086], an inhibitor of reverse transcriptase of HIV, was not significant.This publication has 7 references indexed in Scilit:
- Differential inhibition of various mammalian DNA polymerase activities by ammonium 21‐tungsto‐9‐antimoniate (HPA23)European Journal of Biochemistry, 1988
- Comparative inhibitory effects of suramin and other selected compounds on the infectivity and replication of human T‐cell lymphotropic virus (HTLV‐III)/lymphadenopathy‐associated virus (LAV)International Journal of Cancer, 1986
- Infection of human T-lymphotropic virus type-1 (HTLV-I)-bearing MT-4 cells with HTLV-III (AIDS virus): Chronological studies of early eventsVirology, 1985
- Inhibition of RNA-dependent DNA polymerases of AIDS and SAIDS retroviruses by HPA-23 (ammonium-21-tungsto-9-antimoniate)Annales de l'Institut Pasteur / Virologie, 1985
- Correlation between structure of polyoxotungstates and their inhibitory activity on polymerasesBiochemical and Biophysical Research Communications, 1983
- In vivo Effect of a New Mineral Condensed Ion (HPA 39) on Murine Friend LeukaemiaJournal of General Virology, 1981
- Effects of 5-tungsto-2-antimoniate in oncogenic DNA and RNA virus-cell systemsEuropean Journal of Cancer (1965), 1977