Separation of Enantiomers in Ion-Pair Chromatographic Systems
- 1 February 1986
- journal article
- research article
- Published by Taylor & Francis in Journal of Liquid Chromatography
- Vol. 9 (2-3), 269-290
- https://doi.org/10.1080/01483918608076638
Abstract
Enantiomers of amines and acids have been separated in ion-pair chromatographic systems with chiral agents present in mobile or stationary phase. Chiral counter ions such as quinine or camphorsulfonate have been used in liquid solid systems with organic mobile phases, while the chiral complexing agents albumin and (+)-n-dibutyltartrate have been used in reversed phase systems. Regulation of retention and stereoselectivity as well as improvement of detection sensitivity by the composition of the system is discussed.Keywords
This publication has 16 references indexed in Scilit:
- Chromatographic separation of enantiomers of acids with quinine as chiral counter ionJournal of Chromatography A, 1984
- Chiral resolution of carboxylic and sulphonic acids by ion-pair chromatographyJournal of Chromatography A, 1983
- Normal-phase dynamic (solvent-generated) molecular complexation chromatography using anionic ion exchangersJournal of Chromatography A, 1982
- Über die Enantiomerentrennung durch Verteilung zwischen flüssigen PhasenHelvetica Chimica Acta, 1982
- Separation of optical isomers by zwitterion-pair chromatographyJournal of Chromatography A, 1982
- Retention data methods for the determination of drug-protein binding parameters by high-performance liquid chromatographyJournal of Chromatography A, 1981
- Separation of enantiomeric amines by ion-pair chromatographyJournal of Chromatography A, 1981
- Determination of Tryptophan-Human Serum Albumin Binding from Retention data and Separation of Tryptophan Enantiomer by High Performance Liquid ChromatographyJournal of Liquid Chromatography, 1980
- Stereochemical Aspects of Optical Resolution of Octahedral Metal Chelates by Liquid ChromatographyJournal of Liquid Chromatography, 1979
- 756. The optical resolution of aromatic amino-acids on paper chromatogramsJournal of the Chemical Society, 1952