FATTY ACID SYNTHESIS IN NORMAL AND COLD-ACCLIMATED RATS

Abstract

Rats acclimated to either 0-2[degree]C or 25[degree]C were given glucose-C14 via stomach tube and then sacrificed at 1/2, 1, 6, or 24 hours. The cold-acclimated rats incorporated no more and possibly less C14 into fatty acids than did the rats acclimated to 25 "C. Evidence is presented which indicates that the white adipose tissue probably did not play a quantitatively important role in the conversion of the glucose-C14 to fatty acid. Also, the data indicate that lipogenesis was not a major pathway of the glucose-C14 metabolism.