DOSE-EFFECT RELATIONSHIPS OF EXTRADURAL MORPHINE
Open Access
- 1 December 1982
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 54 (12), 1259-1262
- https://doi.org/10.1093/bja/54.12.1259
Abstract
The effectiveness of three different doses of extradural morphine (4,6 and 8 mg) in relieving post-operative pain was compared in 24 patients. Although there was no significant difference in the efficacy of the three doses, increasing dosage increased the average duration of analgesia provided by the drug (4 mg–593 min; 6 mg–722 min; 8 mg–885 min). All three doses increased the average peak expiratory flow rate, the greatest increases bang seen at the higher dosages. Increasing dosage was not accompanied by an increase in the occurrence of adverse effects.Keywords
This publication has 4 references indexed in Scilit:
- COMPARISON OF FOUR NARCOTIC ANALGESICS FOR EXTRADURAL ANALGESIABritish Journal of Anaesthesia, 1982
- Epidural Narcotics for Postoperative AnalgesiaAnesthesia & Analgesia, 1980
- OBSERVATIONS ON EXTRADURAL MORPHINE ANALGESIA IN VARIOUS PAIN CONDITIONSBritish Journal of Anaesthesia, 1980
- EPIDURAL MORPHINE IN TREATMENT OF PAINThe Lancet, 1979