Testicular Size in Klinefelter's Syndrome in Men over Fifty

Abstract

THE frequency and clinical behavior of Klinefelter's syndrome in infants and young men has been well studied, but little is known of the ultimate course of chromatin-positive males. Few patients over the age of fifty or with a fatal illness have been described. The basis of the diagnosis of Klinefelter's syndrome in young males is the presence of testes with the long diameter measuring less than 3.5 cm. Since no normal data on testicular size in males over fifty have been reported, and the primary basis of diagnosis is therefore unclear, it seems likely that the syndrome often goes undiagnosed, . . .