Endogenous Markers of Two Separate Hypoxia Response Pathways (hypoxia inducible factor 2 alpha and carbonic anhydrase 9) Are Associated With Radiotherapy Failure in Head and Neck Cancer Patients Recruited in the CHART Randomized Trial
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- 10 February 2006
- journal article
- abstracts
- Published by American Society of Clinical Oncology (ASCO) in Journal of Clinical Oncology
- Vol. 24 (5), 727-735
- https://doi.org/10.1200/jco.2005.02.7474
Abstract
Purpose Randomized controlled trials have generally shown a benefit from accelerated radiotherapy in head and neck squamous cell carcinoma (HNSCC). However, the large randomized United Kingdom tria...Keywords
This publication has 33 references indexed in Scilit:
- Differential Roles of Hypoxia-Inducible Factor 1α (HIF-1α) and HIF-2α in Hypoxic Gene RegulationMolecular and Cellular Biology, 2003
- Targeting HIF-1 for cancer therapyNature Reviews Cancer, 2003
- Hypoxia-inducible factors 1?? and 2?? are related to vascular endothelial growth factor expression and a poorer prognosis in nodular malignant melanomas of the skinMelanoma Research, 2003
- Altered fractionation and combined radio-chemotherapy approachesEuropean Journal Of Cancer, 2003
- Hypoxia-Inducible Factor 1α Is Essential for Cell Cycle Arrest during HypoxiaMolecular and Cellular Biology, 2003
- Prognostic impact of reoxygenation in advanced cancer of the head and neck during the initial course of chemoradiation or radiotherapy aloneHead & Neck, 2002
- Association of hypoxia‐inducible factors 1α and 2α with activated angiogenic pathways and prognosis in patients with endometrial carcinomaCancer, 2002
- Hypoxia — a key regulatory factor in tumour growthNature Reviews Cancer, 2002
- Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizersSeminars in Radiation Oncology, 1996
- The potential benefit from a perfect radiosensitizer and its dependence on reoxygenationThe British Journal of Radiology, 1982