Proguanil hydrochloride (paludrine) in the prevention and treatment of malaria in new guinea

Abstract

.Paludrine has proved to be a satisfactory malarial suppressant among the natives but needs reinforcing with quinine to produce the best results among the whites of the area. Paludrine is also excellent for treatment. Five 100 mg. doses given within a 48-hr, period seemed the most effective treatment.