In vitro activity of CP-99,219, a new fluoroquinolone, against clinical isolates of gram-positive bacteria
- 1 February 1993
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 37 (2), 366-370
- https://doi.org/10.1128/aac.37.2.366
Abstract
The in vitro activity of the fluoroquinolone CP-99,219 against gram-positive bacteria was compared with those of five other antimicrobial agents. Against ciprofloxacin-susceptible staphylococci and against streptococci, MICs were < or = 0.12 and < or = 0.5 microgram/ml, respectively. CP-99,219 was also more active than ciprofloxacin against ciprofloxacin-resistant staphylococci, most enterococci, Leuconostoc spp., and lactobacilli.Keywords
This publication has 7 references indexed in Scilit:
- Comparative in vitro activity of PD 127391, a new fluoroquinolone agent, against susceptible and resistant clinical isolates of gram-positive cocciAntimicrobial Agents and Chemotherapy, 1992
- Comparison of Enterococcus raffinosus with Enterococcus avium on the basis of penicillin susceptibility, penicillin-binding protein analysis, and high-level aminoglycoside resistanceAntimicrobial Agents and Chemotherapy, 1991
- Multicenter evaluation of the in vitro activities of three new quinolones, sparfloxacin, CI-960, and PD 131,628, compared with the activity of ciprofloxacin against 5,252 clinical bacterial isolatesAntimicrobial Agents and Chemotherapy, 1991
- Rapid Dissemination of β-Lactamase–Producing, Aminoglycoside-ResistantEnterococcus faecalisamong Patients and Staff on an Infant–Toddler Surgical WardNew England Journal of Medicine, 1990
- Comparative in vitro activity of WIN 57273, a new fluoroquinolone antimicrobial agentAntimicrobial Agents and Chemotherapy, 1990
- Transferable beta-lactamase. A new mechanism for in vitro penicillin resistance in Streptococcus faecalis.Journal of Clinical Investigation, 1983
- In-vitro activity of Sch 29482 in comparison with other oral antibioticsJournal of Antimicrobial Chemotherapy, 1982