An initial report of a phase-III trial comparing vindesine and vincristine for acute lymphocytic leukemia of childhood
- 1 January 1979
- journal article
- research article
- Published by Springer Nature in Cancer Chemotherapy and Pharmacology
- Vol. 2 (4), 267-270
- https://doi.org/10.1007/bf00257193
Abstract
The initial results from the Children's Cancer Study Group (CCSG) study on vindesine are the subject of this report. Vindesine was shown to be active in the treatment of acute lymphocytic leukemia (ALL) in children in a phase-II clinical trial conducted by the CCSG. A phase-III trial is now in progress. The aim of this is to compare the use of vincristine and of vindesine with reference to induction rate, toxicity, and cross-resistance.Keywords
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