Idiopathic Paroxysmal Myoglobinuria with Acute Renal Failure and Hypercalcemia

Abstract

IDIOPATHIC paroxysmal myoglobinuria, variously described as paroxysmal paralytic myoglobinuria, idiopathic recurrent rhabdomyolysis with myoglobinuria and spontaneous myoglobinuria, is a rare disorder of voluntary muscle characterized by episodes of muscle pain and weakness and the passage of myoglobin in the urine. Other rare causes of myoglobinuria such as convulsive attacks, peripheral vascular disease with ischemia, the crush syndrome and electrocution have a visible basis in identifiable muscle damage. Any of these conditions may give rise to renal impairment, and death from acute renal failure may occur.^{1 2 3} In the case presented below, which was of the idiopathic type and not associated with . . .