Environmental Influences on Body Weight and Behavior in Developing Rats After Neonatal 6-Hydroxydopamine
- 8 August 1980
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 209 (4457), 715-717
- https://doi.org/10.1126/science.7394533
Abstract
There is less hyperactive motor activity and better avoidance performance in rat pups treated with 6-hydroxydopamine as neonates and reared with vehicle-treated littermates than in pups reared in litters composed solely of other 6-hydroxydopamine-treated animals. Thus, in this experimental model of hyperactivity, an environmental manipulation provides an alternative to pharmacologic agents in reducing activity and improving learning performance.Keywords
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