Oxidase‐Like Activity of Polymer‐Coated Cerium Oxide Nanoparticles
Top Cited Papers
- 10 March 2009
- journal article
- research article
- Published by Wiley in Angewandte Chemie-International Edition
- Vol. 48 (13), 2308-2312
- https://doi.org/10.1002/anie.200805279
Abstract
Inorganic enzyme? Ceria nanoparticles exhibit unique oxidase‐like activity at acidic pH values. These redox catalysts can be used in immunoassays (ELISA) when modified with targeting ligands (see picture; light blue and yellow structures are nanoparticles with attached ligands). This modification allows both for binding and for detection by the catalytic oxidation of sensitive colorimetric dyes (e.g. TMB).Keywords
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