Stereoselectivity in the Coupling Reaction between 2-Phenylthio-2,3-dideoxyribose and Silylated Pyrimidine Bases
- 1 August 1990
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 19 (8), 1459-1462
- https://doi.org/10.1246/cl.1990.1459
Abstract
Coupling reaction between 2-α-phenylthio-2,3-dideoxyribose and silylated pyrimidine bases in the presence of SnCl4 proceeded stereoselectively to give the β-anomers. These nucleosides were converted to 2′,3′-dideoxy-2′,3′-didehydronucleosides by oxidation followed by thermal elimination.Keywords
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