Abstract
This paper describes a sizeable subgroup of the AIDS caseload that has not been widely studied, that is, men with histories of both male homosexual activity and intravenous drug use. In this paper we identify differences and similarities between gay intravenous drug users and gay men with different histories of drug use; examine the relationship between HIV seropositivity and different patterns of drug use; and estimate whether gay intravenous drug users are more likely than other gay men to be a source of continued HIV transmission.