Abstract
Various authors have reported that alterations in urine volume are associated with alterations in urinary adrenaline and noradrenaline output. (Perman 1961 and Leroy and de Schaepdryver 1961. Weil-Malherbe and Ström-Olsen (1958) reported alterations in urinary adrenaline and noradrenaline excretion associated with mood changes in a group of patients with manic-depressive psychosis. In three of the patients studied, there was also during the manic phase an increased urine volume.